All in all this looks to have been the worst week for the Islamists since May of 2011 when Osama bin Laden was killed and his files and computers were seized in the same raid. For every Saudi/GCC proxy in the area, they're in trouble.
Nusrah Front/al-Qaeda in Syria lost its military commander and another dozen of its regional leaders. Coalition air power was able to act on detailed intelligence reports to hit the right buildings at the exact time Nusrah was having its main planning meeting. As with ISIS